Microbial Genomics: Bioinformatic Analysis Basics
Microbial Genomics: Bioinformatic Analysis Basics
Microbial genomics is revolutionising clinical and public health responses to communicable diseases. Advances in bioinformatics are enabling precise, real-time responses to pathogen outbreaks. This micro-credential is ideal for infectious diseases professionals seeking a strong grounding in bioinformatics concepts and practical experience investigating microbial sequence data. This course is co-designed and…
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COURSE DESCRIPTION
Microbial genomics is revolutionising clinical and public health responses to communicable diseases. Advances in bioinformatics are enabling precise, real-time responses to pathogen outbreaks. This micro-credential is ideal for infectious diseases professionals seeking a strong grounding in bioinformatics concepts and practical experience investigating microbial sequence data. This course is co-designed and delivered in partnership with the Peter Doherty Institute for Infection and Immunity. Understand quality control theory: Understand the importance of sequence data quality control and its impact on data analysis and interpretation in microbial genomics. Explore fundamental bioinformatics theory: Gain a high-level understanding of bioinformatics theory, including the concepts of genome assembly, annotation, genome characterisation, mapping variant calling, and phylogenetics. Gain practical experience in bioinformatics analysis: Analyse sequence data in the online genomics platform, Galaxy. Develop skills to critically assess which analysis approach and bioinformatics tools to use in different scenarios. Apply bioinformatics to interrogate data from real-world case studies: Combine your new theoretical and practical knowledge to assess data and address questions arising from real-world case studies.
Skills and learning outcomes: By the end of this course, you’ll be able to: Explain bioinformatics theory as applied to microbial genomics (with a focus on high-level concepts, quality control and impact on data analysis, and use of pipelines). Explain and undertake genome assembly, annotation and genome characterization analyses (focus on use of these approaches for identifying and investigation of genes and genomic structures, speciation and use of databases); Explain and undertake sequence read mapping and variant calling analyses (with a focus on use of these approaches for identifying and investigating antimicrobial resistance mutations); Explain and undertake basic phylogenetic analyses (focus on use of this approach for outbreak investigation)
EDUCATIONAL INSTITUTION
Established in 1853, the University of Melbourne enjoys an outstanding reputation with world rankings, consistently being placed as Australia’s leading comprehensive research-intensive university, and is one of the world’s top 50 (as per Times Higher Education World University Rankings 2015 – 2016 and Academic Ranking of World Universities 2015). There are over 80 different undergraduate study areas and over 270 graduate courses at Melbourne for students to choose from. The University has extensive global networks and has seven campus locations across Melbourne and rural Victoria.
